CROMG |
Agen, France, 47000 |
Principal Investigator: Olivier Bernard, MD |
Hôpital Privé d'Aix en Provence |
Aix-en-provence, France, 13080 |
Principal Investigator: David COEFFIC, MD |
Centre Hospitalier Général d'Aix-en-Provence |
Aix-en-Provence, France |
Principal Investigator: Sophie Nahon, MD |
CHU Amiens |
Amiens, France |
Principal Investigator: Emma Lachaier, MD. |
Clinique de l'Europe |
Amiens, France |
Principal Investigator: Michel Gozy, MD |
ICO |
Angers, France |
Principal Investigator: Dominique Berton, MD. |
Hôpital Privé d'Antony - Ramsay Santé |
Antony, France, 92160 |
Principal Investigator: Gwen Ael L'HELGOUALC'H, MD |
CH Arras |
Arras, France |
Principal Investigator: Michele Tjean, MD. |
CH Auxerre |
Auxerre, France |
Principal Investigator: Anne-Laure VILLING, MD. |
Institut Sainte Catherine |
Avignon, France |
Principal Investigator: Julien Grenier, MD. |
Clinique Belharra |
Bayonne, France, 64100 |
Principal Investigator: Mathilde DOUBLIER, MD |
CH Côte Basque |
Bayonne, France |
Principal Investigator: Thomas Grellety, MD. |
Centre Hospitalier de Beauvais |
Beauvais, France, 60021 |
Principal Investigator: Daoudia BOULENOUAR, MD |
CHRU Jean Minjoz |
Besançon, France |
Principal Investigator: Elsa Kalbacher, MD. |
CH de Blois |
Blois, France |
Principal Investigator: Olivier Arsene, MD. |
Hôpital Avicenne |
Bobigny, France, 93009 |
Principal Investigator: ZELEK Laurent, MD |
Clinique Tivoli |
Bordeaux, France |
Principal Investigator: Delphine Garbay, MD. |
Hôpital Saint André |
Bordeaux, France |
Principal Investigator: Vanessa Corni, MD. |
Institut Bergonié |
Bordeaux, France |
Principal Investigator: Guillaume BADIN, MD. |
Polyclinique Bordeaux Nord |
Bordeaux, France |
Principal Investigator: Nadine Dohollou, MD. |
CH Bourg en Bresse |
Bourg-en-Bresse, France |
Principal Investigator: Hubert Orfeuvre, MD. |
CHU Brest |
Brest, France |
Principal Investigator: Laura Deiana, MD. |
Hôpital Femme Mère Enfant |
Bron, France, 89500 |
Principal Investigator: Christophe SAJOUS, MD |
Centre François Baclesse |
Caen, France |
Principal Investigator: Pierre-Emmanuel Brachet, MD. |
Centre Maurice Tubiana |
Caen, France |
Principal Investigator: Emmanuel Sevin, MD. |
CH de Cahors |
Cahors, France |
Principal Investigator: Nadia Levasseur, MD. |
CH Castres |
Castres, France |
Principal Investigator: Rodolphe Paulon, MD. |
Medipole de Savoie |
Challes-les-Eaux, France |
Principal Investigator: Dominique Mille, MD. |
CH Chalon sur Saone |
Chalon-sur-Saône, France |
Principal Investigator: Axelle Boudrant, MD. |
Clinique Pôle Léonard de Vinci |
Chambray-lès-Tours, France |
Principal Investigator: Pierre Combe, MD. |
CH Metropole Savoie |
Chambéry, France |
Principal Investigator: Nathalie Marques, MD. |
CH Contentin |
Cherbourg, France |
Principal Investigator: Laure Kaluzinski, MD. |
CH Cholet |
Cholet, France |
Principal Investigator: Alain Zannetti, MD. |
Centre Hospitalier de Chateauroux |
Châteauroux, France, 36000 |
Principal Investigator: François CHRISTIANN, MD |
Hôpital Antoine Béclère |
Clamart, France |
Principal Investigator: Sarah Vieillefosse, MD. |
Centre Jean Perrin |
Clermont-Ferrand, France |
Principal Investigator: Marie-Ange Mouret-Reynier, MD. |
CH Alpes Léman |
Contamine-sur-Arve, France |
Principal Investigator: Mansour Rastkhah, MD. |
Centre Hospitalier Sud Francilien |
Corbeil-Essonnes, France, 91106 |
Principal Investigator: Gilles CALMES, MD |
Clinique des Cèdres |
Cornebarrieu, France, 31700 |
Principal Investigator: Ioana Carpiuc, MD |
GHPSO |
Creil, France |
Principal Investigator: Elisabeth Carola, MD. |
CHI Creteil |
Créteil, France |
Principal Investigator: Zineb Sellam, MD. |
Centre Georges François Leclerc |
Dijon, France |
Principal Investigator: Leïla Bengrine-Lefevre, MD. |
CHU Dijon |
Dijon, France |
Principal Investigator: Marie Chaix, MD |
Centre Hospitalier Intercommunal de Fréjus Saint Raphael |
Fréjus, France, 83600 |
Principal Investigator: Bruno Valenza, MD |
GH Mutualiste de Grenoble |
Grenoble, France |
Principal Investigator: Claire Garnier-Tixidre, MD. |
Hôpital Privé Drôme Ardèche |
Guilherand-Granges, France, 07500 |
Principal Investigator: Louis DOUBLET, MD |
Centre Hospitalier Marne-la-Vallée |
Jossigny, France |
Principal Investigator: Estelle Wafo, MD |
Centre Hospitalier Départemental de Vendée |
La Roche-sur-Yon, France, 85925 |
Principal Investigator: Kristell TAILLANDY-ROY, MD |
CHU Grenoble |
La Tronche, France |
Principal Investigator: Emmanuelle Jacquet, MD. |
CH Versailles |
Le Chesnay, France |
Principal Investigator: Christine Abraham, MD. |
CH Chartres |
Le Coudray, France |
Principal Investigator: Chloé Genet, MD. |
Hôpital privé de l'estuaire |
Le Havre, France, 76600 |
Principal Investigator: Helen HOKOMOS, MD |
CHU Bicêtre |
Le Kremlin-Bicêtre, France |
Principal Investigator: Anne Gaelle POURCELOT, MD. |
Centre Hospitalier du Mans |
Le Mans, France |
Principal Investigator: Mustapha Atlassi, MD |
CH Lens |
Lens, France |
Principal Investigator: Fabienne Watelle, MD. |
Institut Hospitalier Franco-Britannique |
Levallois-Perret, France |
Principal Investigator: Ida Iurisci, MD. |
Polyclinique de Limoges - Clinique Chenieux |
Limoges, France, 87039 |
Principal Investigator: Dominique GENET, MD |
CHU de Limoges |
Limoges, France, 87042 |
Principal Investigator: Tristan GAUTHIER, MD |
GH Bretagne Sud |
Lorient, France |
Principal Investigator: Isabelle Cumin, MD. |
Hôpital de la Croix Rousse |
Lyon, France, 60004 |
Principal Investigator: Charles André PHILIP, MD |
Clinique de l'infirmerie Protestante |
Lyon, France, 69300 |
Principal Investigator: Christine DOLMAZON, MD |
Centre Léon Bérard |
Lyon, France |
Principal Investigator: Isabelle Ray-Cocquard, MD. |
Clinique de la Sauvegarde |
Lyon, France |
Principal Investigator: Yann Molin, MD. |
Hôpital Privé Jean Mermoz |
Lyon, France |
Principal Investigator: Olfa Derbel, MD. |
APHM - Hôpital de la Timone |
Marseille, France |
Principal Investigator: Marie Meurer, MD |
Hôpital Nord |
Marseille, France |
Principal Investigator: Marjorie Baciuchka-Palmaro, MD. |
Institut Paoli Calmettes |
Marseille, France |
Principal Investigator: Renaud Sabatier, MD. |
Centre Hospitalier Layné |
Mont-de-Marsan, France, 40000 |
Principal Investigator: Daniela Petran, MD |
Hôpital Nord Franche Comté |
Montbéliard, France |
Principal Investigator: Fernando Bazan, MD. |
Centre de Cancérologe du Grand Montpellier |
Montpellier, France |
Principal Investigator: Emmanuel Guardiola, MD. |
CHRU de Montpellier - Hôpital Saint-Eloi |
Montpellier, France |
Principal Investigator: Clothilde Lindet-Bourgeois, MD |
ICM - Val d'Aurelle |
Montpellier, France |
Principal Investigator: Pierre-Emmanuel Colombo, PUPH |
CH de Montelimar |
Montélimar, France |
Principal Investigator: Ahmed Azzedine, MD. |
Centre Azuréen de Cancérologie |
Mougins, France, 06250 |
Principal Investigator: Rémy LARGILLIER, MD |
Oracle - Centre d'Oncologie de Gentilly |
Nancy, France |
Principal Investigator: Fabien Brocard, MD. |
Hôpital Foch |
Nanterre, France |
Principal Investigator: Asmahane Benmaziane Teillet, MD. |
Hôpital Privé du Confluent |
Nantes, France |
Principal Investigator: Alain Lortholary, MD. |
Clinique Hartmann |
Neuilly-sur-Seine, France |
Principal Investigator: Jean-Michel Vannetzel, MD. |
Centre Antoine Lacassagne |
Nice, France, 06000 |
Principal Investigator: Philippe Follana, MD |
Institut de Cancérologie du Gard - ONCOGARD |
Nîmes, France, 30029 |
Principal Investigator: Eric LEGOUFFE, MD |
Institut de Cancérologie du Gard |
Nîmes, France |
Principal Investigator: Catherine Marsollier-Ferrer, MD. |
CHR Orléans |
Orléans, France |
Principal Investigator: Jérôme Meunier, MD. |
Hôpital de la Pitié Salpétrière |
Paris, France, 75000 |
Principal Investigator: Johanna Wasserman, MD |
GH Diaconesses |
Paris, France |
Principal Investigator: Frédéric Selle |
GH Saint Joseph |
Paris, France |
Principal Investigator: Robert Sverdlin, MD. |
HEGP |
Paris, France |
Principal Investigator: Anne Sophie Bats, PUPH |
Hôpital Bichat |
Paris, France |
Principal Investigator: Jean-Michel Rodier, MD. |
Hôpital Cochin |
Paris, France |
Principal Investigator: Jérôme Alexandre, MD. |
Hôpital Lariboisière |
Paris, France |
Principal Investigator: Matthieu Mezzadri, MD. |
Institut Curie |
Paris, France |
Principal Investigator: Manuel Rodrigues, MD. |
Institut Mutualiste Montsouris |
Paris, France |
Principal Investigator: Marine Slim, MD. |
CH Pau |
Pau, France |
Principal Investigator: Suzanne Nguyen, MD. |
Centre Catalan d'Oncologie |
Perpignan, France |
Principal Investigator: Stephen Ellis, MD. |
CH Perpignan |
Perpignan, France |
Principal Investigator: Elise Barel, MD. |
Hôpital Lyon Sud |
Pierre-Bénite, France, 69006 |
Principal Investigator: Witold GERTYCH, MD |
Centre CARIO-HPCA |
Plérin, France |
Principal Investigator: Anne-Claire Hardy-Bessard, MD. |
Hôpital de la Milétrie |
Poitiers, France |
Principal Investigator: Cédric Nadeau, MD. |
CH René Dubos |
Pontoise, France |
Principal Investigator: Sabine Assouad, MD. |
CH Annecy Genevois |
Pringy, France |
Principal Investigator: Oana POP, MD. |
Clinique Francheville |
Périgueux, France |
Principal Investigator: Cahrles Briac Levache, MD. |
Clinique de la Croix du Sud |
Quint-Fonsegrives, France |
Principal Investigator: Etienne Suc, MD. |
Institut de Cancer Courlancy |
Reims, France, 51100 |
Principal Investigator: Karinne PRULHIERE-CORVIOLE, MD |
Centre Eugène Marquis |
Rennes, France |
Principal Investigator: Thibault De La Motte Rouge, MD. |
Hôpitaux Drôme Nord - Centre Hospitalier Romans |
Romans-sur-Isère, France, 26100 |
Principal Investigator: Marie Claude Gouttebel, MD |
Centre Henri Becquerel |
Rouen, France, 76000 |
Principal Investigator: Marianne Leheurteur, MD |
Clinique Mathilde |
Rouen, France, 76100 |
Principal Investigator: Marc BARON, MD |
CH Saint Brieuc |
Saint Brieuc, France |
Principal Investigator: Corinne Alleaume, MD. |
Clinique Mutualiste de l'Estuaire |
July 18, 2019
|
July 22, 2019
|
January 29, 2021
|
December 6, 2019
|
December 2029 (Final data collection date for primary outcome measure)
|
Correlation between Progression Free Survival (PFS) and the detected tumor genetic abnormalities [ Time Frame: From baseline until the date of progression or death, which ever occurs earlier, assessed up to 10 years ]
|
Same as current
|
|
- Correlation between age and the detected tumor genetic abnormalities [ Time Frame: Baseline ]
- Correlation between histology status and the detected tumor genetic abnormalities [ Time Frame: Baseline ]
- Correlation between FIGO stage and the detected tumor genetic abnormalities [ Time Frame: Baseline ]
- Correlation between surgery resection status and the detected tumor genetic abnormalities [ Time Frame: Up to 10 years ]
- Correlation between treatment response and the detected tumor genetic abnormalities [ Time Frame: Up to 10 years ]
- Correlation between Overall survival (OS) and the detected tumor genetic abnormalities [ Time Frame: From baseline to death, assessed up to 10 years ]
|
Same as current
|
- Percentage of patients with both germinal and tumoral BRCA tests [ Time Frame: Up to 10 years ]
- Percentage of patients with a first germinal BRCA test, a first tumoral BRCA test, or simultaneous germinal and tumoral tests [ Time Frame: Up to 10 years ]
- Percentage of patients with and exploitable tumoral block for exploratory transversal researches [ Time Frame: Up to 10 years ]
|
Same as current
|
|
Genomic BRCA and Extensive ovArian Cancer Testing
|
Cohort Study to Evaluate the Clinical Features of Patients With Epithelial Ovarian Cancer Depending on Tumoral Mutation of BRCA or Beyond BRCA Genomic Molecular Abnormalities
|
This is a prospective observational French multicenter cohort in patients with ovarian and/or primitive peritoneal and/or fallopian tubes carcinoma, histologically confirmed, with an advanced stage at diagnosis (stage III to IV FIGO 2014). The objective is to constitute a clinico-biological database that allows to correlate clinical and progressive features of ovarian cancer patients based on tumor genomics and molecular detected abnormalities.
|
Not Provided
|
Observational [Patient Registry]
|
Observational Model: Cohort Time Perspective: Prospective
|
10 Years
|
Retention: Samples With DNA Description:
Tumor sample fixed in formalin and included in paraffin (FFPE)
|
Non-Probability Sample
|
Patients with ovarian and/or primitive peritoneal and/or fallopian tubes carcinoma, histologically confirmed, with an advanced stage at diagnosis (stage III to IV FIGO 2014)
|
- Epithelial Ovarian Cancer
- Peritoneal Cancer
- Fallopian Tube Cancer
|
Not Provided
|
Not Provided
|
Not Provided
|
|
Recruiting
|
32
|
4500
|
December 2029
|
December 2029 (Final data collection date for primary outcome measure)
|
Inclusion Criteria:
Exclusion Criteria:
- Patient with a mucinous ovarian carcinoma
- Patient pregnant or breastfeeding
- Patient under legal protection (guardianship or court order) or unable to consent
|
Sexes Eligible for Study: |
Female |
|
18 Years and older (Adult, Older Adult)
|
No
|
Contact: Aurelie Chabanon, PhD. |
+33184852036 |
achabanon@arcagy.org |
|
Contact: Margaux Matos |
+33184852021 ext 01 |
mmatos@arcagy.org |
|
|
France
|
|
|
NCT04027868
|
GINECO-OV128 2019-A01190-57 ( Other Identifier: ANSM ) 19.06.45 ( Other Identifier: Ethics Committee )
|
No
|
Studies a U.S. FDA-regulated Drug Product: |
No |
Studies a U.S. FDA-regulated Device Product: |
No |
|
|
ARCAGY/ GINECO GROUP
|
ARCAGY/ GINECO GROUP
|
AstraZeneca
|
Principal Investigator: |
Thibault De La Motte Rouge, MD. |
Centre Eugène Marquis, Rennes |
|
ARCAGY/ GINECO GROUP
|
May 2020
|