• Serum phosphorus levels [ Time Frame: 12 Weeks ]
  Serum phosphorus levels at the end of treatment;
• The proportion of subjects whose serum phosphorus levels reached the target range. [ Time Frame: 12 Weeks ]
  The proportion of subjects whose serum phosphorus levels reached the target range (3.5 to 5.5 mg/dL, 1.13 to 1.78 mmol/L) at the end of the treatment;
• The response rate of serum phosphorus [ Time Frame: 12 Weeks ]
  The response rate of serum phosphorus at the end of treatment (defined as reduction of the serum phosphorus level exceeds 25% as compared to baseline);
• The change in serum calcium (corrected) levels [ Time Frame: 12 Weeks ]
  The change in serum calcium (corrected) levels at the end of treatment as compared to baseline;
• The change in the [Ca] × [P] product relative [ Time Frame: 12 Weeks ]
  The change in the [Ca] × [P] product relative at the end of treatment as compared to baseline;
• The change in the level of intact-PTH levels [ Time Frame: 12 Weeks ]
  The change in the level of intact-PTH levels at the end of treatment as compared to baseline.

• Hyperphosphatemia
• End Stage Renal Disease
• ESRD

• Drug: Ferric Citrate
  Take the capsules with meals or immediately after meals.
• Drug: Sevelamer Carbonate
  Take the tablets with meals.

• Experimental: Ferric Citrate Capsule
  Ferric Citrate Capsule, product specification: 500 mg/cap, manufactured by Panion & BF Biotech Inc.
  Intervention: Drug: Ferric Citrate
• Active Comparator: Sevelamer Carbonate Tablet
  Sevelamer carbonate tablet group, product specification: 800 mg/tablet, manufactured by Genzyme Ireland Limited
  Intervention: Drug: Sevelamer Carbonate

Inclusion Criteria:

1. Willing to give written informed consent.;
2. Between the age of 18 and 75 years (including the boundary value);
3. Patients who maintain the hemodialysis schedule as 3 times a week and the dialysis schedule should remain unchanged during the study period;
4. At Screening, patients who have received phosphate binder for at least 4 weeks and have a serum phosphorus level between 2.5 and 8.0 mg/dL (0.81 to 2.58 mmol/L) (excluding the boundary value) after treatment;
5. Patients with a serum phosphorus level between 5.5 and 10.0 mg/dL (1.78 to 3.23 mmol/L) (excluding the boundary value) after washout.

Exclusion Criteria:

1. Patients with severe gastrointestinal diseases (such as acute peptic ulcer, chronic ulcerative colitis, regional enteritis, ileus) or patients with dysphagia;
2. Patients with a history of gastrectomy or enterectomy (excluding endoscopic excision or caecectomy) or patients who had undergone gastrointestinal surgery within 3 months prior to Screening;
3. Patients with severe constipation (times of bowel movement≤ 1 time/week), chronic diarrhea (times of bowel movement≥ 4 times/day), severe gastrointestinal motility disorder;
4. Patients with hemochromatosis or patients receiving treatment for iron overload, or patients with a serum ferritin level >800 ng/mL or TSAT >50% at Screening;
5. Patients with a serum calcium level (corrected) <8.0 mg/dL (2.0 mmol/L) or >11.0 mg/dL (2.75 mmol/L) after washout;
6. Patients with intact-PTH>800pg/mL at Screening, or patients undergone parathyroid surgery within 6 months prior to Screening or requiring parathyroid surgery;
7. Patients who received blood transfusions for treating anemia within 3 months prior to Screening;
8. Patients who require phosphorus-binding agents containing aluminum, magnesium, calcium and lanthanum in addition to the study drug or patients who require an antacid with a phosphorus binding effect during the study period;
9. Patients who require citrate preparation as an anticoagulant during hemodialysis treatment during the study period;
10. Patients with impaired liver function (hepatic dysfunction or serum total bilirubin, aspartate aminotransferase or alanine aminotransferase ≥ 2 times the upper limit of normal) or patients with cirrhosis;
11. Patients with cerebrovascular disease (cerebral infarction, cerebral hemorrhage, etc.) or cardiovascular disease (congestive heart failure of Class III or severer in NYHA classification, acute myocardial infarction, unstable angina, etc.) requiring hospitalization within 6 months prior to Screening;
12. Patients who are known to be intolerant to sevelamer carbonate tablet;
13. Patients with a history of allergies to iron preparations or those who are intolerant to iron preparations;
14. Patients who are scheduled to have a kidney transplant during the study period;
15. Patients with a current or past history of malignancy within 5 years prior to Screening;
16. Women who are pregnant or lactating, or patients who are unable to take effective contraception from screening to 6 months after discontinuation (including male subjects and their female spouses);
17. Patients who had participated in other clinical studies and other received investigational drug product within 1 month or 5 half-lives of the drug product (whichever is longer) prior to Screening;
18. Patients who are not suitable for participating in the trial according to the investigator's judgment;
19. Patients who are unwilling or unable to follow the protocol process.