• Visual analogue scale (VAS) of neck pain [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Neck pain intensity for the past 3 days. Total score range: 0 (better outcome) to 100 (worse outcome)
• Visual analogue scale (VAS) of radiating arm pain [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Radiating arm pain intensity for the past 3 days. Total score range: 0 (better outcome) to 100 (worse outcome)
• Neck Disability Index (NDI) [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Functional disability questionnaire. The possible range of each item score is 0 to 5. Total score range: 0 (better outcome) to 50 (worse outcome)
• Patient Global Impression of Change (PGIC) [ Time Frame: Time Frame: 8, 16, 20, 24 weeks, 1, 3, 5 years ]
  Global patient-reported outcome. Total score range: 1 (better outcome) to 7 (worse outcome)
• EuroQol 5-dimensions 5-levels (EQ-5D-5L) [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Health-related quality of life questionnaire. Total score range: 11111 (better outcome) to 55555 (worse outcome)
• Type and frequency of other intervention(s) [ Time Frame: Baseline, 4, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Use of any other additional intervention(s) other than the integrative Korean medicine treatment administered by the attending physician (start date of treatment, end date of treatment, name of treatment, number of treatment sessions received, and other comments)
• Physical examination [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Cervical physical examination
• Type and frequency of adverse reaction(s) [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Safety
• Numeric rating scale (NRS) of Neck pain [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Neck pain intensity for the past 3 days. Total score range: 0 (better outcome) to 10 (worse outcome)
• Numeric rating scale (NRS) of radiating arm pain [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Radiating arm pain intensity for the past 3 days. Total score range: 0 (better outcome) to 10 (worse outcome)
• SF-36 [ Time Frame: Baseline, 4, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  The Short Form (36) Health Survey is a 36-item, patient-reported survey of patient health. The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability.
• EQ-VAS [ Time Frame: [Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years] ]
  The EQ VAS records the respondent's self-rated health on a 20 cm vertical, visual analogue scale with endpoints labelled 'the best health you can imagine' and 'the worst health you can imagine'.

• Visual analogue scale (VAS) of neck pain [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Neck pain intensity for the past 3 days. Total score range: 0 (better outcome) to 100 (worse outcome)
• Visual analogue scale (VAS) of radiating arm pain [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Radiating arm pain intensity for the past 3 days. Total score range: 0 (better outcome) to 100 (worse outcome)
• Neck Disability Index (NDI) [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Functional disability questionnaire. The possible range of each item score is 0 to 5. Total score range: 0 (better outcome) to 50 (worse outcome)
• Northwick Park Neck Pain Questionnaire (NPQ) [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Measures the neck pain and the consequent patient disabilities. The possible range of each item score is 0 to 5. Total score range: 0 (better outcome) to 36 (worse outcome)
• Patient Global Impression of Change (PGIC) [ Time Frame: Time Frame: 8, 16, 20, 24 weeks, 1, 3, 5 years ]
  Global patient-reported outcome. Total score range: 1 (better outcome) to 7 (worse outcome)
• EuroQol 5-dimensions 5-levels (EQ-5D-5L) [ Time Frame: Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Health-related quality of life questionnaire. Total score range: 11111 (better outcome) to 55555 (worse outcome)
• Use of other intervention(s) [ Time Frame: Baseline, 4, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Use of any other additional intervention(s) other than the integrative Korean medicine treatment administered by the attending physician (start date of treatment, end date of treatment, name of treatment, number of treatment sessions received, and other comments)
• Physical examination [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Cervical physical examination
• Adverse reaction [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Safety
• Numeric rating scale (NRS) of Neck pain [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Neck pain intensity for the past 3 days. Total score range: 0 (better outcome) to 10 (worse outcome)
• Numeric rating scale (NRS) of radiating arm pain [ Time Frame: Baseline, 2, 4, 6, 8, 12, 16, 20, 24 weeks, 1, 3, 5 years ]
  Radiating arm pain intensity for the past 3 days. Total score range: 0 (better outcome) to 10 (worse outcome)

• Neck Pain
• Cervical Radiculopathy
• Intervertebral Disc Displacement

• Drug: Herbal medicine
  Herbal medicine will be administered in water-based decoction (120ml) and dried powder (2g) form (Ostericum koreanum,Eucommia ulmoides, canthopanax sessiliflorus, Achyranthes japonica, Psoralea corylifolia, aposhnikovia divaricata, Cibotium barometz, Lycium chinense, Boschniakia rossica, Cuscuta chinensis, Glycinemax, Atractylodes japonica) at the physician's discretion.
  Other Name: Traditional herbal medicine
• Procedure: Chuna manual medicine
  Chuna is a Korean manual therapy directed at the spine and joints that incorporates various spinal manual medicine techniques for joint mobilization involving highvelocity, low amplitude thrusts to joints slightly beyond the passive range of motion and gentle force to joints within the passive range of movement. Chuna manual medicine will be administered to the pelvic, lumbar, thoracic, and cervical vertebrae at the physician's discretion.
  Other Name: Chuna manipulation
• Procedure: Bee venom pharmacopuncture
  Bee venom pharmacopuncture will be administered only after confirming a negative response to hypersensitivity skin test. Diluted bee venom saline:bee venom ratio, 10,000:1) filtered for allergens will usually be injected at 4-5 acupoints proximal to the dysfunctional site at the physician's discretion. Each acupuncture point will be injected to a total of 0.5-1 cc using disposable injection needles (CPL, 1 cc, 26G x 1.5 syringe, hinchang medical co., Korea).
  Other Name: Bee venom acupuncture
• Procedure: Pharmacopuncture
  Pharmacopuncture consisting of select herbal ingredients will be dministered at Hyeopcheok (Huatuo Jiaji, EX B2), Ah-shi points and local acupuncture points using disposable injection needles (CPL, 1 cc, 26G x 1.5 syringe, Shinchang medical co., Korea) at the physician's discretion.
• Procedure: Acupuncture
  Acupuncture treatment will be administered using mainly proximal acupuncture points and Ah-shi points.
• Procedure: Electroacupuncture
  Electroacupuncture treatment will be administered using mainly proximal acupuncture points and Ah-shi points.
• Procedure: Cupping
  Cupping treatment will be administered at 1-2 points using mainly proximal acupuncture points and Ah-shi points.
• Procedure: Other intervention(s)
  Patients will be allowed any other additional intervention(s) as deemed necessary regardless of type or dose, and patterns of use will be investigated and recorded as a pragmatic clinical study.

Inclusion Criteria:

• Patients with age between 19 years ~ 65 years
• Patients with one arm pain or both side arm pain or neck pain with intensity of NRS ≥6 which occurred less then 12 month before
• Patients with cervical radiculopathy symptoms of one or both side of arms
• Patients diagnosed with cervical disc herniation with over protrusion degree of prolapsed inter-vertebral disc assessed on MRI
• Patients with plans of receiving Korean medicine treatment for cervical disc herniation for ≥2 months
• Patients who have agreed to study participation

Exclusion Criteria:

• Patients with other systemic diseases that may interfere with treatment effect or outcome interpretation
• Patients with soft tissue pathologies or pathologies of non-spinal origin that may cause neck pain or radiating arm pain (e.g. spinal tumor, rheumatoid arthritis)
• Patients with medical history of cervical myelopathy which can cause neck pain or radiating arm pain
• Patients with medical history of surgery in relation with cervical disc herniation
• Patients for whom acupuncture treatment may be inappropriate or unsafe (e.g. hemorrhagic diseases, blood clotting disorders, history of anticoagulation medicine intake, serious diabetes with risk of infection, severe cardiovascular diseases, or other conditions deemed unsuitable for acupuncture treatment)
• Pregnant patients or patients planning pregnancy
• Patients with serious psychological disorders
• Patients unable to fill out study participation consent form
• Patients deemed unsuitable for study participation as assessed by the researchers