• Mediation effect [ Time Frame: At 3 months post study ]
  Patient and caregiver symptoms assessed with the MD Anderson Symptom Inventory (MDASI).
• Inflammatory Cytokines [ Time Frame: At 3 months post study ]
  Will be assessed with blood samples.
• Cortisol rhythmicity [ Time Frame: At 3 months post study ]
  Will be assessed via saliva samples.
• Dyadic Symptom Management [ Time Frame: At 3 months post study ]
  Will be assessed with the Couples' Illness Communication Scale (CICS)

PRIMARY OBJECTIVES:

I. To examine the extent to which the yoga program improves patient physical performance (i.e., 6-minute walk test [6MWT]) as compared to the education group.

SECONDARY OBJECTIVES:

I. To examine the extent to which the yoga program improves patient and caregiver quality of life (QOL) (SF-36) compared to the education group.

TERTIARY OBJECTIVES:

I. To explore if, compared to the education group, the yoga program improves symptom burden, reduces inflammatory cytokine and cortisol rhythmicity dysregulation, and improves dyadic symptom management skills at the end of treatment, which will in turn mediate intervention outcomes at the subsequent follow-up assessments.

II. To explore if baseline factors such as depressive symptoms moderate the treatment response.

QUALITATIVE OBJECTIVES:

I. To understand the patient and caregiver experience of cancer, cancer treatment, and experience in the behavioral interventions, and explore emerging themes as possible mediators.

OUTLINE: Patients and caregivers are assigned to 1 of 2 groups.

GROUP I: Patients and caregivers undergo dyadic yoga intervention session involving physical exercises and relaxation techniques over 60 minutes each for up to 15 sessions.

GROUP II: Patients and caregivers undergo dyadic education program session focusing on strategies of how to manage patient and caregiver symptoms over 60 minutes each for up to 15 sessions.

After completion of study, patients and caregivers are followed up every 2 weeks for 3 months and then every month for up to 6 months.

• Caregiver
• Lung Non-Small Cell Carcinoma
• Stage I Lung Cancer AJCC v8
• Stage II Lung Cancer AJCC v8
• Stage IIA Lung Cancer AJCC v8
• Stage IIB Lung Cancer AJCC v8
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8

• Other: Educational Intervention
  Undergo dyadic education program
  Other Names:

  • Education for Intervention
  • Intervention by Education
  • Intervention through Education
  • Intervention, Educational
• Other: Quality-of-Life Assessment
  Ancillary studies
  Other Name: Quality of Life Assessment
• Other: Questionnaire Administration
  Ancillary studies
• Procedure: Yoga
  Undergo dyadic yoga
  Other Name: Yoga Therapy

• Experimental: Group I (dyadic yoga)
  Patients and caregivers undergo dyadic yoga intervention session involving physical exercises and relaxation techniques over 60 minutes each for up to 15 sessions.
  Interventions:

  • Other: Quality-of-Life Assessment
  • Other: Questionnaire Administration
  • Procedure: Yoga
• Active Comparator: Group II (dyadic education)
  Patients and caregivers undergo dyadic education program session focusing on strategies of how to manage patient and caregiver symptoms over 60 minutes each for up to 15 sessions.
  Interventions:

  • Other: Educational Intervention
  • Other: Quality-of-Life Assessment
  • Other: Questionnaire Administration

Inclusion Criteria:

• PATIENT ONLY: Diagnosed with stage I-III non-small cell lung cancer (NSCLC) and going to receive at least 5 weeks of thoracic radiotherapy (RT)
• PATIENT ONLY: Eastern Cooperative Oncology Group (ECOG) performance status of =< 2
• PATIENT ONLY: Having a family caregiver (e.g., spouse, sibling, adult child) willing to participate
• PATIENT AND CAREGIVER: Able to read, write and speak English
• PATIENT AND CAREGIVER: Able to provide informed consent

Exclusion Criteria:

• PATIENT ONLY: Who have regularly (self-defined) participated in a mind-body practice in the year prior to diagnosis